- ￥520 - 10080
- Solarbio
- P00462
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10080.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6240.0 |
| 规格： | 50ug | 产品价格： | ￥1092.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Programmed cell death 1 ligand 1Cd274;programmed cell death 1 ligand 1;PD-L1;PDCD1 ligand 1;programmed death ligand 1;B7 homolog 1;B7-H1;CD274; |
| 中文名称 | Recombinant Mouse PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse Programmed cell death 1 ligand 1(Cd274，PD-L1)，is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner.Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1)，a member of the CD28 family of immunoreceptors.B7-H1 is constitutively expressed in several organs such as heart，skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes.The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation.Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production.The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P00462 Recombinant Mouse PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1 细胞因子/蛋白
￥520 - 10080
