- ￥2210 - 23040
- Solarbio
- P00262
- 北京
- 2025年07月25日
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￥208
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug
| 规格： | 1mg | 产品价格： | ￥23040.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥15360.0 |
| 规格： | 50ug | 产品价格： | ￥2210.0 |
| 基本信息 | |
| 基因名 | |
| 外观(性状) | Supplied as a 0.2 μM filtered solution of PBS, pH 7.4 |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Reconstituted protein solution should be stored at ≤ -20°C.Stable for at least 24 months when stored as instructed. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation，apoptosis，cancer development and progression，and the innate immune response.Known receptors bind S1 are ACE2，angiotensin-converting enzyme 2，DPP4，CEACAM etc.The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits，S1 and S2.S1 mainly contains a receptor binding domain (RBD)，which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses，as well as protective immunity. |
| 单位 | 支 |
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文献和实验ChIP‐chip for Genome‐Wide Analysis of Protein Binding in Mammalian Cells
modification sites along the genome. UNIT 21.9 describes a protocol for analysis of protein?DNA interactions in yeast cells. This unit introduces an alternative protocol developed for mammalian cells. Curr. Protoc. Mol. Biol. 79:21.13.1?21.13.22. © 2007
乙型肝炎、和HBsAg阳性的患者血清中前S1蛋白，前S1抗原阴转愈早，AHB患者的疗程愈短，预后也愈好。说明前S1抗原及其抗体的检测是急性乙型肝炎的临床诊断，疗效观察和判数据预后的良好指标。 前S1蛋白的分子生物学特性 1．乙肝病毒（HBV）的基因结构 HBV为嗜肝DNA病毒，由一个不完全双链DNA组成，约3200个氨基酸。长链L含4个开放读码框架，为病毒蛋白的编码区：S区、C区、P区、X区。短链S相当于长链的50%-100%，其不固定端可被内原性DNA多聚酶延长，使病毒成为完整
, receptor protem; E, effector molecule; α, α-subumt of G protein; βγ, βγ-subunits of G protein; S, substrate, P, product.
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