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- Solarbio
- 北京
- P00257
- 2026年08月13日
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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br> -70°C for 3 months under sterile conditions after redissolves. <br> ≤-70°C, stable for 6 months after receipt.
- 保存条件：
Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br> -70°C for 3 months under sterile conditions after redissolves. <br> ≤-70°C, stable for 6 months after receipt.
- 英文名：
2019-nCoV S Protein RBD
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
50ug/1mg/500ug
| 规格： | 50ug | 产品价格： | ¥2335 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ¥23165 |
| 规格： | 500ug | 产品价格： | ¥15485 |
| 基因名 | 2019-nCoV S Protein RBD |
| 别名 | 2019-nCoV S Protein RBD |
| 蛋白号 | QHD43416.1 |
| 种属 | 2019-nCoV |
| 宿主 | E.coli |
| 产品描述 | Recombinant SARS-CoV-2 S protein RBD Protein is produced by our Mammalian expression system and the target gene encoding Asn331-Val524 is expressed with a mouse IgG1 Fc tag at the C-terminus. |
| 区间范围 | Asn331-Val524 |
| 标签信息 | C-Fc |
| 预测分子量 | 47.9kDa |
| 表观分子量 | 50-60kDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | Not measured |
| 溶剂 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -70°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -70°C for 3 months under sterile conditions after redissolves. ≤-70°C, stable for 6 months after receipt. |
| 运输条件 | 干冰运输（需要收取干冰费） |
| 背景说明 | The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It’s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| 细胞活性 | No activity experimental data, to be verified. |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | No activity experimental data, to be verified. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | 2019-nCoV S Protein RBD |
| 中文名称 | 2019-nCoV S Protein RBD蛋白 |
| 单位 | 支 |
| 规格 | 50ug ; 1mg ; 500ug |
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文献和实验Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60–70% of PS in plasma is noncovalently bound to C4-binding protein (C4BP). Free PS functions as a cofactor that enhances the activity of activated protein C (APC
Analysis of the Protein S Gene in Protein S Deficiency
Protein S (PS) is a 71-kDa vitamin K-dependent glycoprotein first identified in human plasma by DiScipio and colleagues in 1977 (1 ), a year after the discovery of the anticoagulant protein C (PC) (2 ,3 ). A few years later, Walker
, both the intact rBoNTC(Hc)-C and the rBoNTC(Hc )-N missing the first eight amino acids of the N-terminus have vaccine potency; consequently, partial degradation did not have an impact on these protein’s utility.
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