- ￥520 - 10080
- Solarbio
- P00519
- 北京
- 2025年07月25日
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￥520
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10080.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6240.0 |
| 规格： | 50ug | 产品价格： | ￥1092.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Cyclin-dependent kinase 2-associated protein 2;CDK2-associated protein 2;DOC-1-related protein;DOC-1R;CDK2AP2;DOC1R |
| 中文名称 | Recombinant Human Cyclin-dependent kinase 2-associated protein 2/CDK2AP2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CDK2AP2，also known as DOC1R，is short for cyclin-dependent kinase 2-associated protein 2.The gene CDK2AP2 encodes this protein that interacts with cyclin-dependent kinase 2 associated protein 1.Pseudogenes associated with this gene are located on chromosomes 7 and 9.Alternatively spliced transcript variants have been observed for this gene.It belongs to the CDK2AP family.CDK2AP1 (cyclin-dependent kinase 2-associated protein 1)，corresponding to the gene doc-1 (deleted in oral cancer 1)，is a tumor suppressor protein.The doc-1 gene is absent or down-regulated in hamster oral cancer cells and in many other cancer cell types.The ubiquitously expressed CDK2AP1 protein is the only known specific inhibitor of CDK2，making it an important component of cell cycle regulation during G(1)-to-S phase transition. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Assays for Cyclin-Dependent Kinase Inhibitors
Cyclin-dependent kinases (CDK) are serine/threonine kinases that regulate cell cycle control and progression (1 ,2 ). A CDK holoenzyme complex is active if associated with its cyclin partner and if the complex is phosphorylated at specific
Detection of DNA-Dependent Protein Kinase in Extracts from Human and Rodent Cells
The DNA-dependent protein kinase, DNA-PK, is required for DNA double-strand break repair and V(D)J recombination (1 –3 ). DNA-PK is composed of a large catalytic subunit of approx 460 kDa (DNA-PKcs) and a heterodimeric DNA targeting subunit
Measurement of Changes in Cdk2 and Cyclin O-Associated Kinase Activity in Apoptosis
is stimulus-specific because it occurs in glucocorticoid and DNA damage but not in CD95-induced apoptosis in thymocytes. Apoptotic Cdk2 activation in lymphoid cells is controlled by a recently identified protein, cyclin O, and its activity is modulated by p53
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