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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥5200.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥3640.0 |
| 规格: | 50ug | 产品价格: | ¥832.0 |
| 规格: | 10ug | 产品价格: | ¥312.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ubiquitin-Conjugating Enzyme E2 S;E2-EPF;Ubiquitin Carrier Protein S;Ubiquitin-Conjugating Enzyme E2-24 kDa;Ubiquitin-Conjugating Enzyme E2-EPF5;Ubiquitin-Protein Ligase S;UBE2S;E2EPF |
| 中文名称 | Recombinant Human UBE2S/Ubiquitin-conjugating enzyme E2 S |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family.UBE2S interacts with CDC20,FZR1/CDH1 and VHL.UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner,a characteristic property of Ubiquitin Carrier Proteins.UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome,a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis.UBE2S is also involved in ubiquitination and subsequent degradation of VHL,resulting in an accumulation of HIF1A. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Studies of the Ubiquitin Proteasome System
in Insect Cells Using a Baculovirus System Alternate Protocol 11: Preparation of Rabbit E1 Support Protocol 4: Generation of Empty Bacterial Lysates Generation of Ubiquitin‐Conjugating Enzymes (E2s) Basic Protocol 22: Expression of E2s in E. coli
Proteasomes that Lack Endogenous USP14 and are Devoid of UB‐AMC Hydrolysis Activity Support Protocol 2: Purification of Recombinant Human USP14 from E. coli Support Protocol 3: Synthesis and Purification of Ubiquitin
P is the catalytic subunit of the enzyme. Cell. 1983, 35 (3 Pt 2): 849-57. PMID 6197186. ^ (英文)1989年度诺贝尔化学奖 ^ 3.0 3.1 (英文)Jarrous N, Reiner R. Human RNase P: a tRNA-processing enzyme and transcription factor. Nucleic Acids Res.. 2007, 35
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