- ￥312 - 6912
- Solarbio
- P00173
- 北京
- 2025年07月25日
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￥832
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥6912.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥4680.0 |
| 规格： | 50ug | 产品价格： | ￥832.0 |
| 规格： | 10ug | 产品价格： | ￥312.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA4;CD152 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Cytotoxic Tlymphocyte 4(CTLA-4，CD152)，is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence，a 126 aa extracellular domain (ECD) with one Ig-like V-type domain，a 21 aa transmembrane (TM) sequence，and a 41 aa cytoplasmic sequence.It is widely expressed with highest levels in lymphoid tissues.CD28 and CTLA-4，together with their ligands，B7-1 and B7-2，constitute one of the dominant costimulatory pathways that regulate T and B cell responses.CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily.CTLA4 transmits an inhibitory signal to T cells，whereas CD28 transmits a stimulatory signal.Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions.Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4. |
| 来源 | Human cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Methods for Human CD8+ T Lymphocyte Proteome Analysis
T lymphocytes, including cytotoxic CD8+ T cells, are important cells involved in immunology, as they can destroy infected or tumor cells. We describe here a detailed protocol starting from CD8+ T lymphocytes isolation for T cell culture followed
The transfer of homozygous C57Bl/6 (B6) or DBA/2 (DBA) parental strain T cells into normal B6D2F1 mice in the parent-into-F1 (p → F1) model results in a graft-vs.-host disease (GVHD) that takes one of the following two forms: (a) acute GVHD
randomly paired light (L) and heavy (H) chain coding regions under transcriptional control of P lac . The H chain coding region is fused in-frame with the phage gene, Δ gIII , coding for a truncated version of the phage surface protein pIII (ΔpIII
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