- ￥1092 - 21120
- Solarbio
- P00147
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
Recombinant Human R-spondin-1 is produced by our Mammalian expression system and the target gene encoding Arg31-Ala263 is expressed with a 6His tag at the C-terminus.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
成员:Deyu Zhang, Songze Song, Jing Lin, Tianxing Ye, Xiao Yang, Qiwei Jiang, Yue Mi, Mengting Zhang, Xiangwei Ge, Yanjie Shen, Peizhe Du, Yanzhu Shi, Xiujuan Zhang, Ling Li, Yanan Zhang, Lihua Ding, Jie Liu, Youzhi Zhang, Shan Gao, Qinong Ye
论文因子:10.7 发表期刊:DEVELOPMENTAL CELL pmid:40086433
| 基本信息 | |
| 基因名 | |
| 别名 | RSPO1;R-spondin1;RP11-566C13.1;CRISTIN3;FLJ40906;RSPO Rspo1;R-spondin;Rspondin;RP23-325M14.2;Roof plate-specific spondin-1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | RSPO1 is a secreted protein，containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family.RSPO1 is required for the early development of gonads，regardless of sex.It has been found in mice only eleven days after fertilization.To induce cell proliferation，it acts synergistically with WNT4.They help stabilize β catenin，which activates downstream targets.RSPO1 is necessary in female sex development.It augments the WNT/β catenin pathway to oppose male sex development.In critical gonadal stages，between six and nine weeks after fertilization，the ovaries upregulate it while the testes downregulate it.RSPO1 can potentially aid in the treatment of mucositis，which is characterized by inflammation of the oral cavity.This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors. |
| 来源 | Human cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
成员:Deyu Zhang, Songze Song, Jing Lin, Tianxing Ye, Xiao Yang, Qiwei Jiang, Yue Mi, Mengting Zhang, Xiangwei Ge, Yanjie Shen, Peizhe Du, Yanzhu Shi, Xiujuan Zhang, Ling Li, Yanan Zhang, Lihua Ding, Jie Liu, Youzhi Zhang, Shan Gao, Qinong Ye
论文因子:10.7 发表期刊:DEVELOPMENTAL CELL pmid:40086433
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