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P00135 Recombinant Human BTLA

/B-andT-lymphocyte attenuator/CD272(Fc fusion) 细胞因子/蛋白
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  • ¥1560 - 23040
  • Solarbio已认证
  • P00135
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥23040.0
    规格:500ug产品价格:¥16128.0
    规格:50ug产品价格:¥4576.0
    规格:10ug产品价格:¥1560.0
    Recombinant Human B- and T-Lymphocyte Attenuator is produced by our Mammalian expression system and the target gene encoding Lys31-Leu150 is expressed with a Fc tag at the C-terminus.
    基本信息
    基因名
    别名B- and T-Lymphocyte Attenuator;B- and T-Lymphocyte-Associated Protein;CD272;BTLA
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Powder:<-20℃ for long store;RT,3 weeks.Liquid:4-7℃,2-7 days;<-20℃,3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain.BTLA expression is induced during activation of T cells,and BTLA remains expressed on Th1 cells but not Th2 cells.Like PD1 and CTLA4,BTLA interacts with a B7 homolog,B7H4.However,unlike PD-1 and CTLA-4,BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R),not just the B7 family of cell surface receptors.BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response.BTLA also is a ligand for tumor necrosis factor (receptor) superfamily,member 14 (TNFRSF14),also known as herpes virus entry mediator (HVEM).BTLA-HVEM complexes negatively regulate T-cell immune responses.
    来源Human cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
    单位

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