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P00084 Recombinant Human B7-2

/CD86 细胞因子/蛋白
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  • ¥520 - 15360
  • Solarbio已认证
  • P00084
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10752.0
    规格:50ug产品价格:¥1560.0
    规格:10ug产品价格:¥520.0

    Recombinant Human CD86 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro247 is expressed with a 6His tag at the C-terminus.

    基本信息
    基因名
    别名T-Lymphocyte Activation Antigen CD86;Activation B7-2 Antigen;B70;BU63;CTLA-4 Counter-Receptor B7.2;FUN-1;CD86;CD28LG2
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production,by binding CD28 or CTLA-4.It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells,such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.Isoform 2 interferes with the formation of CD86 clusters,and thus acts as a negative regulator of T-cell activation.The protein interacts with MARCH8,human herpesvirus 8 MIR2 protein,adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.
    来源Human cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
    单位

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