- ￥1560 - 29280
- Solarbio
- P00055
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥29280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥18300.0 |
| 规格： | 50ug | 产品价格： | ￥4576.0 |
| 规格： | 10ug | 产品价格： | ￥1560.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-31;IL-31;IL31 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure.It shares several structural and functional characteristics with IL-6，Oncostatin M，LIF，and Cardiotrophin-1.Human IL-31 cDNA encodes a 164 amino acid precursor that contains a 23 amino acid signal peptide and a 141 amino acid mature protein.Human and mouse IL-31 share 24% sequence identity in the mature region.IL-31 is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2).IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM Rβ).The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFNγ on monocytes.GPL/OSMR signaling is a strong activator of STAT3 and STAT5，and can also activate STAT1，Jak1，and Jak2 signaling pathways.IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.Studies have shown that IL31 induces severe pruritis (itching) and dermatitis in transgenic mice. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
31 Inverse PCR: Genomic DNA Cloning
DNA sequence information using this technique. Some recombinant phage or plasmids may be unstable in bacteria and amplified libraries tend to lose them. IPCR eliminates this problem. Fig. 1. Diagram of IPCR for genomic DNA cloning
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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