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P00346 Recombinant Human UBE2G

2/Ubiquitin-conjugating enzyme E2 G2 细胞因子/蛋白
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  • ¥312 - 5200
  • Solarbio已认证
  • P00346
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥5200.0
    规格:500ug产品价格:¥3640.0
    规格:50ug产品价格:¥832.0
    规格:10ug产品价格:¥312.0
    基本信息
    基因名
    别名Ubiquitin-Conjugating Enzyme E2 G2;Ubiquitin Carrier Protein G2;Ubiquitin-Protein Ligase G2;UBE2G2
    中文名称Recombinant Human UBE2G2/Ubiquitin-conjugating enzyme E2 G2
    外观(性状)Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    运输条件干冰运输
    背景说明Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation,which belong to the ubiquitin-conjugating enzyme family.It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively.The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins.The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate.The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s.
    来源E.coli
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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