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- 详细信息
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥5200.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥3640.0 |
| 规格: | 50ug | 产品价格: | ¥832.0 |
| 规格: | 10ug | 产品价格: | ¥312.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ubiquitin-Conjugating Enzyme E2 G2;Ubiquitin Carrier Protein G2;Ubiquitin-Protein Ligase G2;UBE2G2 |
| 中文名称 | Recombinant Human UBE2G2/Ubiquitin-conjugating enzyme E2 G2 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation,which belong to the ubiquitin-conjugating enzyme family.It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively.The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins.The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate.The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P00346 Recombinant Human UBE2G2/Ubiquitin-conjugating enzyme E2 G2 细胞因子/蛋白
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