- ¥520 - 16896
- Solarbio
- 北京
- P00044
- 2026年08月13日
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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
IL-17A
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ¥520.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥1560.00 |
| 规格： | 500ug | 产品价格： | ¥11808.00 |
| 规格： | 1mg | 产品价格： | ¥16896.00 |
| 基因名 | IL-17A |
| 别名 | Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; IL17A; CTLA8; IL17 |
| 蛋白号 | Q16552 |
| 种属 | Human |
| 宿主 | E.coli |
| 产品描述 | Recombinant Human Interleukin-17A is produced by our E.coli expression system and the target gene encoding Gly24-Ala155 is expressed. |
| 区间范围 | Gly24-Ala155 |
| 标签信息 | Tag free |
| 预测分子量 | 16 kDa |
| 表观分子量 | 16 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <1EU/ug as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation. |
| 细胞活性 | Measured by its ability to induce IL-6 secretion by NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1-7 ng/ml. |
| ELISA活性 | Immobilized Human IL-17A at 2μg/ml (100μl/wel) can bind Anti-Human IL-17A mAb.The ED50 of Anti-Human IL-17A mAb is 0.185 ug/ml. |
| SPR/BLI活性 | Loaded Biotinylated Human IL-17RA-His-Avi on HIS1K Biosensor, can bind Human IL-17A with an affinity constant of 0.50 nM as determined in BLI assay. |
| 研究领域 | 炎症与免疫调节 |
| 英文名称 | IL-17A |
| 中文名称 | IL-17A蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
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