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- 2025年07月25日
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- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥16896.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥11808.0 |
| 规格： | 50ug | 产品价格： | ￥1560.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
Recombinant Human Interleukin-17A is produced by our E.coli expression system and the target gene encoding Ile20-Ala155 is expressed.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Downregulation of Cathepsin B Reduces Proliferation and Inflammatory Response and Facilitates Differentiation in Human HaCaT Keratinocytes, Ameliorating IL-17A and SAA-Induced Psoriasis-Like Lesion
成员:Xu Di, Wang Jie
论文因子:4.092 发表期刊:INFLAMMATION pmid:34037897
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression
成员:Zhang Lihua, Guo Hui, Zhang Xiaoguang, Wang Ling, Wei Feng, Zhao Yike, Wang Bo, Meng Yibo, Li Yanling
论文因子:2.9 发表期刊:FUNCTIONAL & INTEGRATIVE GENOMICS pmid:38240925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-17A;IL-17;IL-17A;Cytotoxic T-Lymphocyte-Associated Antigen 8;CTLA-8;IL17A;CTLA8;IL17 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells.There are at least six members of the IL-17 family in humans and in mice.As IL-17 shares properties with IL-1 and TNF-alpha，it may induce joint inflammation and bone and cartilage destruction.This cytokine is found in synovial fluids of patients with rheumatoid arthritis，and produced by rheumatoid arthritis synovium.It increases IL-6 production，induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage.IL-17 is also able to increase bone destruction and reduce its formation.Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Downregulation of Cathepsin B Reduces Proliferation and Inflammatory Response and Facilitates Differentiation in Human HaCaT Keratinocytes, Ameliorating IL-17A and SAA-Induced Psoriasis-Like Lesion
成员:Xu Di, Wang Jie
论文因子:4.092 发表期刊:INFLAMMATION pmid:34037897
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression
成员:Zhang Lihua, Guo Hui, Zhang Xiaoguang, Wang Ling, Wei Feng, Zhao Yike, Wang Bo, Meng Yibo, Li Yanling
论文因子:2.9 发表期刊:FUNCTIONAL & INTEGRATIVE GENOMICS pmid:38240925
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis
成员:Luting Yang, Jie Zhang, Chunqing Hu, Xiaowen Chen, Yang Yang, Huihao Tang, Xiaolei Ding, Yaping Yan
论文因子:3.6 发表期刊:EXPERIMENTAL DERMATOLOGY pmid:37688280
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
CUSABIO季度文献盘点：二季度新增600篇产品引用文献，总文献数量已达 31400篇！
感谢您一直以来对华美生物CUSABIO的支持！2026年二季度，CUSABIO产品发表文献新增600篇！总文献数量已达 31400篇！感谢您在科研旅程中，选择了CUSABIO科研试剂，再次感谢您对我们的信任与支持，我们将不断努力，为您提供更好的产品和服务！下面就让我们一起来分享一下大家精彩的研究成果吧~ 2026 CUSABIO季度文献盘点 01 标题：PRELP negatively regulates IL-17A
回收率优于商业试剂盒。该方法亦适用于tdRFP报告小鼠——在EAE模型中，91%的中枢浸润CD4⁺ T细胞仍保持RFP阳性，并可同步检测RORγt、IL-17A和T-bet表达。 完整操作流程 本研究推荐一套标准化流程，用于在保留荧光报告蛋白的同时高效染色转录因子或细胞因子。 若需检测细胞因子 先用PMA（50 ng/mL）和离子霉素（500 ng/mL）刺激细胞4小时，并加入布雷菲德菌素A（1 μg/mL）阻断蛋白
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