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- Solarbio
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- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥16896.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥11808.0 |
| 规格： | 50ug | 产品价格： | ￥4576.0 |
| 规格： | 10ug | 产品价格： | ￥1560.0 |
Recombinant Human Granulocyte Colony-Stimulating Factor is produced by our E.coli expression system and the target gene encoding Thr31-Pro204 is expressed.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Combination regimen of granulocyte colony-stimulating factor and recombinant human thrombopoietin improves the curative effect on elderly patients with leukemia through inducing pyroptosis and ferroptosis of leukemia cells
成员:Wang Xiaobin, Liu Xiaoyu, Wang Huihan
论文因子:5.854 发表期刊:CANCER GENE THERAPY pmid:35768562
| 基本信息 | |
| 基因名 | |
| 别名 | Granulocyte Colony-Stimulating Factor;G-CSF;Pluripoietin;Filgrastim;Lenograstim;CSF3;C17orf33;GCSF |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol,pH 4.0. |
| 纯度 | ED50 is less than 0.1ng/ml. Specific Activity of 6.0×107 IU/mg.measured by the dose-dependent proliferation of murine NFS-60 indicator cells.≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 区间范围 | MTPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLY QGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRV LRHLAQP |
| 背景说明 | Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds.It induces the survival，proliferation，and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils.Among the family of colony-stimulating factors，G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.The synthesis of G-CSF can be induced by bacterial endotoxins，TNF，Interleukin-1，and GM-CSF.Prostaglandin E2 inhibits the synthesis of G-CSF.In epithelial，endothelial，and fibroblastic cells secretion of GCSF is induced by Interleukin-17. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in16X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug). |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Combination regimen of granulocyte colony-stimulating factor and recombinant human thrombopoietin improves the curative effect on elderly patients with leukemia through inducing pyroptosis and ferroptosis of leukemia cells
成员:Wang Xiaobin, Liu Xiaoyu, Wang Huihan
论文因子:5.854 发表期刊:CANCER GENE THERAPY pmid:35768562
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