P00026 Recombinant Human IL-18

Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encodingTyr37-Asp193 is expressed.

基本信息
基因名
别名	Interleukin-18;Iboctadekin;Interferon gamma-inducing factor;IFN-gamma-inducing factor;Interleukin-1 gamma;IL-1 gamma;GIF;IL-18;IL-1g;IL1F4;MGC12320
外观(性状)	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.Less than 0.1 ng/g (1 IEU/g).
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
区间范围	YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMN PPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
背景说明	Interleukin-18 is a secreted protein and it belongs to the IL-1 family.IL-18 is a proinflammatory cytokine and produced by macrophages and other cells.This cytokine can induce the IFN-gamma production of T cells.The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production，and enhance IgG2a production of B cells.IL-18 binding protein (IL18BP) can specifically interact with this cytokine，and thus negatively regulate its biological activity.After stimulation with IL-18，natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.
来源	E.coli
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 8X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
单位	支