2,2-Bis(hydroxymethyl-d2)propi

Genomic Strategies for the Identification of Dopamine Receptor Genes in Zebrafish

that yielded contig segments of several D2-like DR genes. From these sequences, we amplified full-length cDNAs encoding three D2, one D3, and three D4 DR receptor subtypes via RT-PCR. The predicted proteins displayed 57–72% amino acid identity when compared

Functional Analysis of Human D1 and D5 Dopaminergic G Protein-Coupled Receptors: Lessons from Mutagenesis of a Conserved Serine Residue in the Cytosol

In mammals, dopamine G protein-coupled receptors (GPCR) are segregated into two categories: D1-like (D1R and D5R) and D2-like (D2Rshort , D2Rlong , D3R, and D4R) subtypes. D1R and D5R are primarily coupled to stimulatory heterotrimeric GTP

Application of TaqMan RT-PCR for Real-Time Semiquantitative Analysis of Gene Expression in the Striatum

including vanilloid receptors (5 ) and two pore potassium channels (6 ). More specifically, TaqMan RT-PCR studies have demonstrated a huge enrichment of dopamine D2 (7 ) and D3 (8 ) receptors in human striatal tissues compared to other brain regions