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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2
- 抗体英文名:
Phospho-VEGF Receptor 2-Y1175 antibody
- 抗体名:
Phospho-VEGF Receptor 2-Y1175 antibody
- 规格:
100μl
Phospho-VEGF Receptor 2-Y1175 antibody
Product Name Phospho-VEGF Receptor 2-Y1175 antibody
Catalog No PAab09964
Packing 100ul
Form liquid
Alternative Name CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Immunogen A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
IHC use Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using PAab09964 at dilution of 1:50
WB use
HUVE cells were subjected to SDS PAGE followed by western blot with PAab09964 at dilution of 1:600
Protein Information
Gene ID 3791
Uniprot ID P35968
Calculated MW 250 kDa
Research Area
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