- ￥2260
- LSM Bio
- 进口
- PAab10030
- 2025年07月16日
- ELISA, WB
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
linker for activation of T cells
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
linker for activation of T cells
- 抗体英文名：
LAT antibody
- 抗体名：
LAT antibody
- 规格：
100μl
LAT antibody
Product Name LAT antibody
Catalog No PAab10030
Packing 100ul
Form liquid
Alternative Name LAT, LAT1, p36 38, pp36
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Immunogen linker for activation of T cells
Specificity Human
Tested Application ELISA, WB
Recommended dilution WB: 1:500 - 1:2000
IHC use
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab10030(LAT antibody) at dilution of 1:1000
Protein Information
Gene ID 27040
Uniprot ID O43561
Calculated MW 36-38 kDa
Research Area Immunology, Signal Transduction
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文献和实验人 T 细胞活化连接蛋白(LAT) 酶联免疫分析（ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 T 细胞活化连接蛋白(LAT) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本 中人 T 细胞活化连接蛋白(LAT) 水平。用纯化的 人 T 细胞活化连接蛋白(LAT) 抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中加入 T 细胞活化连接蛋白(LAT
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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