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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ABCB1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IP, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ABCB1
- 抗体英文名:
P Glycoprotein antibody
- 抗体名:
P Glycoprotein antibody
- 规格:
100μl
P Glycoprotein antibody
Product Name P Glycoprotein antibody
Catalog No PAab09805
Packing 100ul
Form liquid
Alternative Name ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
Immunogen ABCB1
Specificity Human, Mouse
Tested Application ELISA, WB, IP, IHC
Recommended dilution WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09805(P glycoprotein antibody) at dilution of 1:500
WB use
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09805(P glycoprotein antibody) at dilution of 1:300
Protein Information
Gene ID
Uniprot ID P08183
Calculated MW 173 kDa
Research Area Neuroscience, Immunology, Metabolism
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文献和实验Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays
) antibodies and anti-beta 2 glycoprotein I (β2-GPI) antibodies. Other autoantibodies, such as those directed against anionic phospholipids, can also be assayed; however they are not of clinical significance. Participation in a quality assurance
Single Primer ("Semi-Random") P
cresol red 2. T/TS 10.5 µL EDB 1 µL Taq Polymerase (Promega) @ 5 u/µL 1 µL TaqStart antibody (CloneTech) as delivered 3. EDB 2.5 mg/ml bovine serum albumin in 10 mM Tris, pH 8.3 References 1. S.R.J.A.M. Hermann
【分享】Glycoprotein Analysis in Biomedicine
Spectrometry of Glycoprotein Oligosaccharides Gunnar Hansson; Hasse Karlsson pp. 47-54 5. Microscale Sequencing of N-Linked Oligosaccharides of Glycoproteins Using Hydrazinolysis, Bio-Gel P-4, and Sequential Exoglycosidase Digestion Tsuguo Mizuochi pp
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