- ￥2260
- LSM Bio
- 进口
- PAab09428
- 2025年07月15日
- ELISA,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
vacuolar protein sorting 16 homolog (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
O95498
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
vacuolar protein sorting 16 homolog (S. cerevisiae)
- 抗体英文名：
anti-VPS16 antibody,VPS16 antibody
- 抗体名：
anti-VPS16 抗体,VPS16 抗体
- 规格：
100μl
VPS16抗体| VPS16 antibody
货号 PAab09428
蛋白别名 HVPS16 antibody, VPS16
蛋白介绍
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruitment of VPS33A to the HOPS complex (PubMed:23901104). Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS33A but not VPS33B (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).
产品描述
anti-VPS16 antibody is a Rabbit Polyclonal antibody againstVPS16..
建议稀释比例
WB :1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000
IHC
Immunohistochemistry of paraffin-embedded human liver using PAab09428(VPS16 antibody) at dilution of 1:100
Western blot
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09428(VPS16 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
""> ""> ""> ""> ""> "">风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验
技术资料暂无技术资料 索取技术资料
