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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原:
interleukin 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
interleukin 2
- 抗体英文名:
IL2 antibody
- 抗体名:
IL2 antibody
- 规格:
100μl
IL2 antibody
Product Name IL2 antibody
Catalog No PAab09820
Packing 100ul
Form liquid
Alternative Name Aldesleukin, IL 2, IL2, interleukin 2, lymphokine, T cell growth factor, TCGF
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Immunogen interleukin 2
Specificity Human
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09820( IL2 antibody) at dilution of 1:100
WB use
MCF-7 cells were subjected to SDS PAGE followed by western blot with PAab09820 at dilution of 1:1000
Protein Information
Gene ID 3558
Uniprot ID P60568
Calculated MW 22 kDa
Research Area Immunology, Cardiovascular, Signal Transduction
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文献和实验Antibody-IL2 Fusion Proteins for Tumor Targeting
as part of an antibody-cytokine fusion protein to the tumor tissue by a single chain fragment of variable regions (scFv) antibody recognizing a tumor-associated antigen. IL2 can moreover be combined with IL12 in a dual cytokine fusion protein, which simultaneously
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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