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文献和实验雄激素 androgen 由精巢提取的睾酮一类的具有雄性激素作用的物质之总称,由 19个碳原子构成的雄烷基本结构的类固醇也称为雄激素。主要的天然雄激素如下表所示。雄激素的作用,通常是以未成熟的或去势的大鼠的精囊、前列腺等重量的增加,或孵化后鸡雏的鸡冠重量的增加作为检验的指标。雄激素多具有促进氮素同化作用。
Androgen Action During Prostate Carcinogenesis
Androgens are critical for normal prostate development and function, as well as prostate cancer initiation and progression. Androgens function mainly by regulating target gene expression through the androgen receptor (AR). Many studies
Analysis of Androgen Receptor SUMOylation
Androgen receptor (AR) is a ligand-controlled transcription factor that is deregulated and therefore targeted in prostate cancer. In addition to androgens, AR is regulated by post-translational modifications (PTMs). SUMOylation, conjugation
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