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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
ACTH [1-39] Peptide (Rat)
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | ACTH [1-39] Peptide (Rat) |
| 产品链接: | http://www.abbiotec.com/peptides/acth-%25255B1-39%25255D%25252C-rat |
| 货号: | 350025 |
| 规格: | 1 mg |
| 产品描述: | Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress. ACTH secretion is triggered by the corticotropin-releasing hormone (CRH) released from the hypothalamus, and stimulates the adrenal glands to release corticosteroids such as cortisol. ACTH [1-39] corresponds to full-length ACTH. ACTH [1-24] is conserved across species and is 75% as potent as ACTH. ACTH [1-10] has no ACTH activity but alter blood pressure. ACTH [4-10] has neurological effects. |
| 序列: | Rat: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH or H-SYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEF-OH |
| 分子式: | C210H315N57O57S |
| 分子量: | 4582.26 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Adrenocorticotropic hormone; ACTH; corticotropin |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Amyloid -Peptide Neurotoxicity Assay Using Cultured Rat Cortical Neurons
of neurotrophic factors. This chapter presents a detailed protocol for the preparation of rat and mouse cortical and hippocampal neuron cell cultures, using either embryonic or postnatal tissue.
Functional Identification of Peptide Receptors
. More recently, the dramatic development of genetic engineering has contributed to revealing the structure of complete genes coding for known, as well as novel, biologically active peptides, in addition to a large number of other peptide sequences of unknown
促肾上腺皮质激素(adrenocorticotropichor-mone,ACTH)
垂体前叶分泌的一种激素,能促进皮质激素的产生。其化学成分是39个氨基酸组成的单链多肽,分子量4500道尔顿。不同种属动物ACTH氨基酸组成略有差异。腺垂体中贮存ACTH量很少,人垂体约含ACTH50单位(0.25毫克活性肽),每天分泌1~5单位(5~25微克),紧张情况下分泌量增加。循环中ACTH半衰期短,人约10~25分钟,血浆中ACTH有昼夜规律变化,上午6~8时为高峰,下午6~11时最低。其生理作用为促肾上腺皮质增生,促肾上腺皮质激素合成与释放。糖皮质激素无论是安静
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