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- BioLegend
- 142105
- 美国
- 2025年07月09日
- 大鼠
- 小鼠
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- 技术资料
- 抗体名：
APC anti-mouse TIGIT (Vstm3)
- 抗体英文名：
APC anti-mouse TIGIT (Vstm3)
- 浓度：
0.2 mg/ml
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
大鼠
- 保质期：
2-3年左右
- 适应物种：
小鼠
- 标记物：
APC
- 克隆性：
单克隆
- 形态：
液体
- 规格：
25ug
APC anti-mouse TIGIT (Vstm3) Antibody
1G9
Catalog# / Size 142105 / 25 µg
142106 / 100 µg
Clone
Regulatory Status RUO
Other Names VSIG9
Isotype Mouse IgG1, κ
Description T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as V-set and
transmembrane domain-containing protein 3 (Vstm3), is a 26 kD, type I transmembrane protein
and member of the CD28 family. TIGIT is expressed on activated T cells, follicular T helper,
memory, and regulatory T cells as well as on NK cells. Its binding partners include CD155 (PVR)
and CD112 (PVRL2). TIGIT is a negative regulator of NK and T cell activation. Engagement of
TIGIT by dendritic cells results in their differentiation into a tolerogenic phenotype, with an
increased secretion of IL-10 and a diminished production of IL-12. Mice deficient for TIGIT are
more susceptible to autoimmune disease.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Mouse
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with APC under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged
exposure to light. Do not freeze.
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