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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
PE anti-mouse FcεRIα
- 抗体英文名:
PE anti-mouse FcεRIα
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
Armenian Hamster
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
Armenian Hamster
- 适应物种:
小鼠
- 标记物:
PE
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
50ug
PE anti-mouse FcεRIα Antibody
MAR-1
Catalog# / Size 134307 / 50 µg
134308 / 200 µg
Clone
Regulatory Status RUO
Other Names FceRIa, FceRI-α, high affinity IgE receptor
Isotype Armenian Hamster IgG
Description FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric
complex with one β and two γ-subunits. The FcεRI complex plays an important role in
triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils
and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and
basophils release bioactive chemical mediators such as histamine, resulting in the initiation of
allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers
immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with
the FcεRIα subunit.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Armenian Hamster
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with PE under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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