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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
APC anti-mouse IL-17A
- 抗体英文名:
APC anti-mouse IL-17A
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
APC
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
100 μg
APC anti-mouse IL-17A Antibody
TC11-18H10.1
Catalog# / Size 506915 / 25 µg
506916 / 100 µg
Clone
Regulatory Status RUO
Other Names Interleukin-17, Cytotoxic T lymphocyte-associated antigen 8 (CTLA-8)
Isotype Rat IgG1, κ
Description IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high
degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is
produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17
have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological
activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts,
activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory
mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal
antibody is able to ameliorate the disease course.
Product Details
Isotype Control APC Rat IgG1, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen E. coli expressed, recombinant mouse IL-17A
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with APC under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The IL-17A antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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