- ￥5557.50
- 华韵生物(Huayunbio)
- HFC4099-100Tests
- 2025年07月13日
- FCM
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
12个月
- 供应商：
广州华韵生物科技有限公司
- 应用范围：
FCM
- 规格：
100Tests
请联系华韵客服获取说明书。
产品简介：
| Background |
FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.
|
| Alternate Names |
IPEX; JM2; Scurfin; Zinc finger protein JM2;Forkhead box protein P3
|
| Swissprot |
Q99JB6
|
| Gene ID |
20371
|
| Clone No |
FJK-16s
|
| Host |
Rat
|
| Reactivity |
Mouse;Rat
|
| Application |
ICFCM
|
| Isotype |
Rat IgG2a, κ
|
| Isotype Control |
PE/Elab Fluor® 594 Rat IgG2a, κ Isotype Control[2A3]
|
| Conjugation |
PE/Elab Fluor594
|
| Conjugation Information |
PE/Elab Fluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
|
| Spectrum |
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验Intracellular Immunofluorescent Staining for Flow Cytometry
9 Human CTLA-4 (CD152) 14D3 Mouse/Human/Rat Cytochrome C 6H2 Human Foxp3 PCH101 Mouse Foxp3 FJK-16s Mouse/Human Granzyme B
)Secondary Antibody15mlIHC-P8125SSignalStain® Boost IHC Detection Reagent (HRP, Mouse)Secondary Antibody15mlIHC-P8889SAnti-rabbit IgG (H+L), F(ab')2 Fragment (Alexa Fluor® 594 Conjugate)Secondary Antibody250µlIF-IC F8890SAnti-mouse IgG (H+L), F(ab
secondary antibody review -- data from 99 publications
Signaling 18 IgG Alexa Fluor 488 immunocytochemistry 1:2000 18 IgG Alexa Fluor 568 immunocytochemistry 1:2000 19 donkey IgG HRP western blot 1:3000 detect antibody binding in mouse epithelial cells Amersham Biosciences 19 goat
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