- 询价
- Hello Bio
- 英国
- HB0355
- 2025年10月24日
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- 详细信息
- 技术资料
- 保存条件：
Room temperature
- 英文名：
Kainic acid
- 供应商：
Hello Bio
- CAS号：
487-79-6
- 规格：
10mg///25mg///50mg///100mg
Kainic acid is the prototypic, selective kainate receptor (KAR) agonist. Analog of L-Glutamate.
Kainic acid is a potent excitant and neurotoxin (shows ~30-fold more neurotoxic potency than L-Glutamate).
It induces various changes in vivo including recurrent seizures, behavioural changes, oxidative stress, glial activation and selective neuronal death.
Kainic acid exerts its neuroexcitatory action by binding to glutamate receptors to cause Ca2+ influx and triggering subsequent excitotoxic neuronal death pathway cascades.
It is widely used to model various neurodegenerative diseases and epilepsy.
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