Immunotag™ Human NLR family CA

Immunity：厦门大学韩家淮团队揭示 PELO 控制 NOD 样受体家族蛋白寡聚化组装和激活的机制

(Nucleotide-binding and oligomerization domain, NOD 或 NACHT) ；除 NLRP10 外，所有 NLR 蛋白的 C 端都含有亮氨酸重复序列  (leucine-rich repeat, LRR)，而其 N 末端则由各异的蛋白相互作用结构域构成，如 CARD、PYD 结构域等【3】。大量研究表明，依赖 NACHT 结构域介导的寡聚化是 NLR 蛋白激活的共同特征和主要方式；但目前人们对 NLR 家族蛋白寡聚化组装激活的机制并不清楚。 2023 年 3 月 21

Detection of a Lipid-Lysine Adduct Family with an Amide Bond as the Linkage: Novel Markers for Lipid-Derived Protein Modifications

An amide-type adduct, hexanoyl-lysine (HEL) is generated from the reaction between n-6 fatty acid (FA)-derived lipid peroxide and lysine. Immunochemical and chemical methods can be used to detect the formation of HEL. For example, an ELISA

Isolate It All：siRNA • miRNA • Total RNA • Native Protein

expression levels from the same experimental sample. Two Kits in One To isolate protein, small RNA and long RNA species from the same sample, Ambion scientists have developed a unique tool: the mir Vana™ PARIS™ Kit . Quantitative recovery of small