Spacer Phosphoramidite C6

Manual Oligonucleotide Synthesis Using the Phosphoramidite Method

or iso -butyryl amides. The 3′-OH group of the first nucleoside is attached to the solid support by a spacer chain, and the synthesis procedes by coupling the 5′-OH group of the growing chain to the 3′-phosphorus of the monomer being added

Synthesis and Application of Highly Reactive Amino Linkers for Functional Oligonucleotides

): N ‐Benzoyl‐2′‐deoxyadenosine phosphoramidite N ‐Benzoyl‐2′‐deoxycytidine phosphoramidite or N ‐Acetyl‐2′‐deoxycytidine phosphoramidite

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

Nagatsugi, F., Uemura, K., Nakashima, S., Maeda, M., and Sasaki, S. 1997. 2‐Aminopurine derivatives with C6‐substituted olefin as novel cross‐linking agents and the synthesis of the corresponding β‐phosphoramidite precursors. Tetrahedron 53:3035‐3044