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- 2026年03月27日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental
- 库存：
复苏：1-2周。冻存：现货。（建议:复苏为主，极个别特殊情况选冻存）
- 供应商：
上海富衡生物科技有限公司
- 肿瘤类型：
神经母细胞瘤
- 细胞类型：
真核细胞
- 品系：
人源神经母细胞瘤细胞系
- 组织来源：
骨髓
- 相关疾病：
神经母细胞瘤（常用于神经发育研究）
- 物种来源：
人源
- 免疫类型：
非免疫细胞
- 细胞形态：
上皮样
- 是否是肿瘤细胞：
是
- 器官来源：
神经组织
- 运输方式：
常温/干冰，快递运输
- 年限：
数年
- 生长状态：
贴壁生长
- 规格：
1 × 10⁶ cells/T25 flask/冻存管
| 规格： | 1 × 10⁶ cells/T25 flask | 产品价格： | ￥1200.0 |
|---|---|---|---|
| 规格： | 冻存管 | 产品价格： | ￥1500.0 |
SH - SY5Y 细胞在神经科学研究领域应用广泛，常被用于神经退行性疾病、神经发育以及药物研发等方面的研究，有助于深入了解神经母细胞瘤的发病机制和探索相关治疗策略。
| 产品名称 | 人神经母细胞瘤细胞；SH-SY5Y(STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | SH-SY5Y |
| 货号 | FH0156 |
| 规格 | 1 × 10⁶ cells/T25 flask |
| 培养 | DMEM + 10% FBS + 1% P/S |
| 别称 | SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental |
| 形态特征 | 上皮样 |
| 生长特性 | 贴壁生长 |
| 培养基 | SH-SY5Y完全培养基 |
| 培养条件 | 气相：95% 空气，5% CO₂；温度：37 ℃ |
| 传代方法 | 1:2传代 |
| 组织来源 | 骨髓 |
| 产品分类 | 人源细胞系 |
| 特别声明 | 富衡细胞库承诺尽最大努力对实验细胞资源相关信息进行及时更新。但限于当时的技术条件，细胞库资料不保证其准确性。 |
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文献和实验| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
| Identification of the disulfidptosis-related gene IQGAP1 as a potential diagnostic biomarker in Parkinson’s disease | 10.1016/j.brainres.2026.150153 | 2026-01-06 | BRAIN RESEARCH | 2.6 | Jianlin Li, Jianhang You, Zaipu Li, Jing Zang, Lin Wu, Tao Zhao |
| Hypoxia-induced LONP1 overexpression and mtDNA damage may serve as biomarkers for death from mechanical asphyxia | 10.1016/j.legalmed.2025.102769 | 2025-12-24 | Legal Medicine | 1.4 | Tianpu Wu, Heng Zhang, Dongchuan Zhang, Yikai Hu, Lu Tian, Wencan Li, Fu Zhang, Bi Xiao, Jianlong Ma, Yi Shi, Yue Chen, Hanfeng Jiang, Xinbiao Liao, Kaijun Ma, Long Chen |
| SIRT2-mediated autophagy as a target of Butylphthalide in the treatment of ischemic stroke | 10.1016/j.bbrc.2025.152588 | 2025-09-03 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2.2 | Hai-Qian Zhou, Hai-Tao Gao, Wen-Mei Lu, Wen-Liang Jiang, Dan-Hong Wu |
| Atractylenolide III Mitigates Alzheimer's Disease by Enhancing Autophagy via the YY1-TFEB Pathway | 10.1002/ptr.70069 | 2025-08-20 | PHYTOTHERAPY RESEARCH | 6.3 | Xiaowei Zhang, Shuang Chu, Yanli Huang, Zhonghua Li, Junying Song, Pan Wang, Yunfang Su, Zhenqiang Zhang, Zhishen Xie |
| Blue Honeysuckle (Lonicera caerulea L.)-anthocyanins and Cyanidin-3-O-glucoside Protect Dopaminergic Neurons Against Ferroptosis by Activating the Nrf2-GPX7 Axis | 10.1016/j.freeradbiomed.2025.07.038 | 2025-07-28 | FREE RADICAL BIOLOGY AND MEDICINE | 8.2 | Xiao-Na Li, Li-Li Fan, Qian Zhu, Jia-Hui Liu, Zhen-Yan Xie, Jia-Lin Cao, Jun-Yu Tan, Li Lin, Xue-Song Li, Xin-Hua Wei |
| P2X7R activation promotes ferroptosis in dopaminergic neurons via NF-κB signaling pathway in vitro and in vivo models of MPP+/MPTP-induced Parkinson’s disease | 10.1016/j.brainres.2025.149824 | 2025-07-08 | BRAIN RESEARCH | 2.6 | Yao Si, Shi Yan, Xueying Li, Wencai Ding, Xinyu Zhang, Kejuan Jia, Lifen Yao, Fan Yang, Wanying Shi |
| Endoplasmic Reticulum Stress Inhibition Promotes Mitophagy via Miro1 Reduction to Rescue Mitochondrial Dysfunction and Protect Dopamine Neurons in Parkinson’s Disease | 10.1007/s10571-025-01575-9 | 2025-05-29 | CELLULAR AND MOLECULAR NEUROBIOLOGY | 4.8 | Wen Yuqi, Han Zheng, Wang Bao, Feng Chenxi, Ding Xvshen, Li Yangni, Lv Yan, Wang Xuelian, Gao Li |
| Ultrasmall Nanoparticles Mitigate Tau Hyperphosphorylation to Restore Synaptic Integrity and Boost Cognitive Function in Alzheimer's Disease | 10.1002/adhm.202500941 | 2025-05-16 | Advanced Healthcare Materials | 9.6 | Hanbing Xu, Gang Wang, Zhilin Jiang, Yaobao Han, Weiming Zhao, Hao Zhang, Hong Liu, Huayue Liu, Zhen Li, Fuhai Ji |
| Minocycline nanoplatform penetrates the BBB and enables the targeted treatment of Parkinson's disease with cognitive impairment | 10.1016/j.jconrel.2024.11.066 | 2024-11-29 | JOURNAL OF CONTROLLED RELEASE | 10.5 | Guowang Cheng, Zhiwen Liu, Zhao Yan, Jiaxin Wu, Zilin Li, Sijia Gao, Chunye Zheng, Shuanshuan Guo, Yue Pan, Xiaojia Chen, Guanghui Lin, Jianhua Zhou, Tongkai Chen |
| Identification of copper metabolism-related markers in Parkinson’s disease | 10.1080/07853890.2024.2425064 | 2024-11-18 | ANNALS OF MEDICINE | 4.9 | Jie Lin, Guifeng Zhang, Bo Lou, Yi Sun, Xiaodong Jia, Meidan Wang, Jing Zhou, Zhangyong Xia |
| UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease | 10.1155/2024/2550642 | 2024-07-25 | Applied Bionics and Biomechanics | 1.8 | Minghua Xu, Xiaomin Zhao, Jiang Zhao, Zhisheng Tan, Chengshi Zhang, Yun Huang, Huiping Zhong, Meifeng Guo, Chen Zhang, Ping Ye, Wentao Zheng |
| Sensitizing TRAIL response via differential modulation of anti- and pro-apoptotic factors by AZD5582 combined with ER nanosomal TRAIL in neuroblastoma | 10.1016/j.acthis.2022.151856 | 2022-01-22 | ACTA HISTOCHEMICA | 2.1 | Chaohong Huang, Yujie He, Jianwu Sun, Qian Yuan, Shuyi Li, Huan Hou, Kui Su, Changhong Ke, Zhiyun Du, Zhengqiang Yuan |
| Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib | 10.3390/cancers12051157 | 2020-05-04 | Cancers | 6.1 | Changhong Ke, Huan Hou, Jiayu Li, Kui Su, Chaohong Huang, Yue Lin, Zhiqiang Lu, Zhiyun Du, Wen Tan, Zhengqiang Yuan |
polymorphic Y chromosome-specific short tandem repeats (STRs) have been described and a set of 9 loci were selected, considered as the minimal haplotype included in the forensic databases, Y-STR Haplotype Reference Databases, the largest now available online
Constructing STR Multiplex Assays
Multiplex polymerase chain reaction (PCR) refers to the simultaneous amplification of multiple regions of deoxyribonucleic acid (DNA) using PCR. Commercial short tandem repeat (STR) assays that can coamplify as many as 16 different loci
据统计约 30% 细胞系被交叉污染或错误辨识，因使用了交叉污染或错误辨识的细胞而导致研究结论错误、结果不可重复、临床细胞治疗灾难性后果……，这浪费大量时间、精力和金钱。Everything was going along fine until they discovered their HeLa cell line expressed Y chromosome markers因此近年 NIH、ATCC、Nature 和 Science 等对此多次发出呼吁，要求研究者对细胞进行鉴定。STR 基因
