Recombinant protein of human c

gene_symbol：CX3CL1
Description：Recombinant protein of human chemokine (C-X3-C motif) ligand 1 (CX3CL1)
Accn：NM_002996
Unipro ID：P78423
Synonyms：ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1
Species：Human
Amount：10 ug
Delivery time：2周
Expression sequence：Gln25-Arg339
Tags：C-His
PredictedMW：34.4 kDa
Buffer：Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Stability：Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity
Purity：>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration：lot specific
Preparation
Endotoxin：< 0.1 EU per µg protein as determined by LAL test
Shipping
Background：This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]