PCNA (1-261) human recombinant

gene_symbol：PCNA
Description：PCNA (1-261) human recombinant protein, 0.1 mg
Accn：NM_002592
Unipro ID：P12004
Synonyms：Cyclin
Species：Human
Amount：100 ug
Delivery time：详询
Expression sequence：MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S
Tags
PredictedMW：28 kDa
Buffer：Presentation State: PurifiedState: Liquid purified proteinBuffer System: 20 mM Tris-HCl, pH 7.5 containing 2 mM EDTA and 20% Glycerol
Stability：Shelf life: one year from despatch.
Bioactivity
Purity：>95% by SDS PAGE
Concentration：lot specific
Preparation：Liquid purified protein
Endotoxin
Shipping
Background：The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]