Working anti-human IgG (Fc)-FI

Quantification of Human IgG and Related Fc Fusion Proteins by a Human IgG/Fc Capture ELISA

of recombinant human IgGs after production and purification for further assays. Here, we describe a human IgG/Fc capture enzyme linked immunosorbent assay (ELISA) which is simple, robust, inexpensive and specific for all types of human IgGs and related Fc fusion

免疫球蛋白Fc段受体FcαR

层细胞高表达FcRn，可介导母体血中IgG进入胎儿血循环；通过肠上皮的FcRn，可将母体初乳中IgG转运到新生儿血循环。将人IgG通过肠道上皮细胞转运到肠腔结合相应的抗原，然后又将IgG／抗原复合物通过肠上皮细胞屏障又转运回黏膜固有层，被DC所加工，并提呈给局淋巴样组织中CD4+T细胞，表明IgG也是黏膜表面重要的免疫分子。       ②Fcα/μR，一种新的既可结合IgA又可结合IgM的Fc受体，人Fcα/μR基因与pIgR相邻。成熟Fcα/μR为单链跨膜蛋白，胞膜外区有3个结构

Transient Production of scFv-Fc Fusion Proteins in Mammalian Cells

Single chain Fv (scFv) antibody fragments fused to the human immunoglobulin G (IgG) Fc moiety obtain IgG-like properties, but nevertheless they are still encoded by a single gene. As transient production of scFv-Fc proteins in mammalians