Recombinant-Gamma-secretase-su
bunit-pen-2pen-2Gamma-secretase subunit pen-2 Alternative name(s): Presenilin enhancer protein 2- ￥9674
- CUSABIO
- CN
- CSB-CF880030CXY
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
"-20°C/-80°C"
- 保质期：
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
- 英文名：
Customized Caenorhabditis elegans pen-2 Protein (in vitro E.coli)
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 规格：
20ug
Alternative Name(s)
Gamma-secretase subunit pen-2 Alternative name(s): Presenilin enhancer protein 2Editorial/Sponsord
EditorialUniprot ID
Q9U357Gene Names
pen-2Organism
Caenorhabditis elegansAASequence
MDISKLTDVKKVDLCKKYFLIGACFLPLVWIVNTFWFFSDAFCKPINAHRRQIRKYVIAS IVGSIFWIIVLSAWEIFFQHYRAQGLVWTDFLTFVFPTGRVExpression Region
1-101aaSequence Info
Full lengthSource
in vitro E.coliSource Notice
Mammalian cell expression systems and other species are available. Please inquire.Tag Info
InquireMW
InquireList Price
1382Purity
Greater than 85% as determined by SDS-PAGE.Storage Buffer
Tris/PBS-based buffer, 6% TrehaloseStorage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.Endotoxin
Not Test. Endotoxin removal service is available for free upon you request.产品类型
Transmembrane-Protein备注
**产品信息可能有变动，请以官网信息为准
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文献和实验**产品信息可能有变动，请以官网信息为准
with the recommended amount of ATP, 2 μl of gamma-33P-ATP (20 μCi), and 2 μl of purified enzyme (10 units of cAMP-dependent protein kinase (catalytic subunit), 1000 units of casein kinase II, or 100 units of Erk2). Following the 1 hr incubation, the slides were washed
-2R (IL-2 Receptor) alpha subunit primarily increases the affinity of ligand binding and is not known to contain a signaling domain, whereas the beta and gamma subunits participate in both ligand binding and signal transduction (Ref.1). The IL-2R signaling
分，分别是可溶性的 sAPPβ 和膜结合的 C99 片段 (CTFβ)。 • 第二步：γ-分泌酶复合物登场。这个复合物由 PS1/PS2、NCT、PEN2、APH1 四种蛋白组成，它会进一步切割 C99 片段，最终产生两种产物：Aβ 蛋白和 APP 胞内结构域 (AICD)[1]。 图 1. Aβ 的产生[1]。 新生成的 Aβ 蛋白单体并不安分，它们会自发“抱团”。先是组装成可溶性的 Aβ 寡聚体 (AβOs) 和原纤维，最终聚集形成不溶性的纤维沉淀，也就是我们常说的 Aβ 斑块。 值得
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