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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Mucin-17 (MUC17), partial (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human Mucin-17 (MUC17), partial (Active)品名简称:
Recombinant Human MUC17 protein, partial (Active)货号:
CSB-MP727848HU规格:
20μg价格:
1140LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 95% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Measured by its binding ability in a functional ELISA. Immobilized Human MUC17 at 2 μg/mL can bind Anti-MUC17 recombinant antibody (CSB-RA727848MA1HU), the EC50 is 0.9057-1.259 ng/mL.基因名:
MUC17Uniprot No.:
Q685J3别名:
(MUC-17)(Small intestinal mucin-3)(MUC-3)种属:
Homo sapiens (Human)蛋白长度:
Partial来源:
Mammalian cell分子量:
32.0 kDa表达区域:
4131-4390aa氨基酸序列:
RTTTCFGDGCQNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTVTVTSVKFTEELKNHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLRLGSVVVEHDVLLRTKYTPEYKTVLDNATEVVKEKITKVTTQQIMINDICSDMMCFNTTGTQVQNITVTQYDPEEDCRKMAKEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQMSLSGPQCLCVTTETHWYSGETCNQGTQKSL蛋白标签:
C-terminal 10xHis-tagged产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Probably plays a role in maintaining homeostasis on mucosal surfaces.功能2:
/文献:
Probably plays a role in maintaining homeostasis on mucosal surfaces.研究领域:
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文献和实验: CSB-BP619964 HU >> Baculovirus CSB-MP619964 HU >> Mammalian cell PD1 多克隆抗体 Rabbit anti PD1 货号:CSB-PA619964LA01 HU 识别种属:human,mouse 应用检测:WB、IHC、IF 等 TIM3 重组蛋白 货号:CSB-EP010145 HU TIM3 多克
来源、不同分化阶段的细胞可表达不同的分化抗原。利用人黑色素瘤特异的CTL克隆已鉴定出多种黑色素细胞分化抗原,这些抗原在多种黑色素瘤细胞呈异常表达,但在正常黑色素细胞仅呈轻微表达。现已发现的Pmel17 gpl00、酪氨酸酶和Melan-AMART-1 等分化抗原在黑色素瘤细胞中呈高表达,而且不同患者的黑色素瘤的分化抗原的结构高度同源,即很少显示个体差异,其机制可能涉及黑色素瘤细胞在生长发育的特定阶段,发生基因的异常性激活或调节基因发生突变,引起编码蛋白异常表达和细胞恶性转化。这些异常表达的分化
合成肿瘤抗原小肽用于肿瘤的免疫治疗。目前已鉴定出一批与人MHC I类分子结合的肿瘤抗原小肽,用人工合成的一些抗原小肽,在临床研究中已产生效果。 粘蛋白MUC-I作为肿瘤抗原与前面所述的不同,它激活T细胞不受MHC限制。粘蛋白MUC-I,又称为上皮细胞粘蛋白(epithelial cell mucin)、多肽性上皮粘蛋白(polymorphic epithelial mucin)或episialin。MUC-I表达于腺上皮细胞,通过其羧基端的疏水性穿膜区与细胞膜连接,其胞外区很长,由1000
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