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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
艾美捷科技
- 英文名:
BCMA CHO Recombinant Cell Line (High Expression)
- 规格:
2 vials
BCMA CHO 重组细胞系(高表达),BCMA CHO Recombinant Cell Line (High Expression) ,BCMA CHO 重组细胞系(高表达),BCMA CHO Recombinant Cell Line (High Expression)
BCMA CHO 重组细胞系(高表达)-BCMA CHO Recombinant Cell Line (High Expression)
产品货号:BPS-79500-H
产品规格:2 vials

B细胞成熟抗原(BCMA)又称肿瘤坏死因子受体超家族成员17(TNFRSF17),是tnfrsf17基因编码的一种蛋白质。Tnfrsf17是识别b细胞活化因子(BAFF)的TNF受体超家族的细胞表面受体。BCMA优先在成熟b淋巴细胞和多发性骨髓瘤(MM)细胞中表达。CART-BCMA是由慢病毒介导的自体转基因t细胞产物,表达完全人类bcma特异性嵌合抗原受体。针对BCMA的CARt细胞具有临床前抗mm活性,2017年,FDA批准BCMACARt细胞免疫疗法在多发性骨髓瘤中的突破性指定。

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