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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
InVivoMAb Anti-Mouse PD-1 & PD-L1 Bispecific Antibody (Iv0240)
- 抗体英文名:
InVivoMAb Anti-Mouse PD-1 & PD-L1 Bispecific Antibody (Iv0240)
- 浓度:
1 mg/ml
- 应用范围:
FuncS
- 宿主:
Mouse
- 适应物种:
Mouse
- 保质期:
1 year
- 级别:
科研级
- 库存:
999
- 供应商:
AntibodySystem
- 克隆性:
Monoclonal
- 亚型:
IgG
- 规格:
100ug

| 宿主 | Mouse |
| 种属反应性 | Mouse |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 浓度 | 1 mg/ml |
| 纯度 | >95% as determined by SDS-PAGE. |
| 克隆类型 | Monoclonal |
| 同种型 | IgG |
| 应用 | FuncS |
| 靶标 | Bispecific, Programmed cell death protein 1, Protein PD-1, mPD-1, CD279, Pdcd1, Pd1, Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1 |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | Q02242 & Q9EP73 |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 克隆号 | Iv0240 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
Currently, AntibodySystem's product lines cover multiple research areas, including 48 types of viruses and superbugs, parasites, tumors, Alzheimer's disease, Parkinson's disease, hypersensitivity and allergic reactions, immune suppression, and immune activation.
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文献和实验How to Make Bispecific Antibodies
of two molecules of Fab’-A(mal) with two free SH-groups at the hinge of a single Fab’-B molecule (see Note 3 ). The remaining free SH groups on Fab’-B are alkylated, and the F(ab’)2 bispecific antibody product (Fab’-A x Fab’-B) is separated by gel filtration
[欢迎下载]:Antibody Engineering: Methods and Protocols
11 Selection of Internalizing Antibodies for Drug Delivery 12 Engineering Multivalent Antibody Fragments for In Vivo Targeting 13 Production of Recombinant Bispecific Antibodies 14 Expression and Isolation of Recombinant Antibody Fragments in E
中科院高福院士课题组 2020 年发表了哪些重要的研究成果?
抗体 523-11 形成复合物。RABV-G 具有三个结构域,碱性至酸性 pH 值变化会导致较大的结构域重新定向和伴随的结构域 - 接头重建,从而将其从弯曲的发夹构型转变为延伸的构型。在这种低 pH 诱导的结构转变过程中,发现位于域连接子中的残基在糖蛋白介导的膜融合中起重要作用。最后,该抗体主要通过其重链与 RABV-G 相互作用,并与病毒蛋白中的二聚体构象表位结合以进行中和。这些结构为疫苗和药物设计提供了有价值的信息。 图源:Cell Host & Microbe 3、发现,PD-1、PD-L1 普遍
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