庆大霉素硫酸盐 *Sigma货号：G1264-250MG

一般描述

化学结构：氨基糖苷类 庆大霉素，也称为庆大霉素C，是一种由革兰氏阴性菌天然产生的氨基糖苷
该抗生素可通过阻止蛋白质合成而发挥作用
[1]硫酸庆大霉素可在体内和体外阻止革兰氏阳性菌和革兰氏阴性菌的生长
在组织培养中，硫酸庆大霉素可用于抑制各种支原体菌株的生长
[2] 应用
Penicillin sulfate is a broad-spectrum antibiotic that has been used as a selector (anti gentamicin gene) in cell culture and molecular biology experiments. The recommended concentration for product use is 50mg/mL

Biochemical/physiological effects

Mechanism of action: Penicillin binds to the 30S ribose subunit, causing codon misreading and hindering the transfer of peptidyl transferase from the donor site to the recipient site. Penicillin exerts its bactericidal effect on Pseudomonas aeruginosa by binding to the outer membrane, replacing natural cations on the outer membrane, making the membrane unstable, and forming pores on the cell surface Antibacterial spectrum: including Gram negative and Gram positive bacteria, including resistance to tetracycline, chloramphenicol, kanamycin, and colistin, certain specific strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus