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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Interleukin-17F protein (IL17F) (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
5μg
英文名称:
Recombinant Human Interleukin-17F protein (IL17F) (Active)品名简称:
Recombinant Human IL17F protein (Active)货号:
CSB-AP001841HU规格:
5μg价格:
852LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
>95% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.基因名:
IL17FUniprot No.:
Q96PD4别名:
IL-17F,种属:
Homo sapiens (Human)蛋白长度:
Full Length of Mature Protein来源:
E.Coli分子量:
15 kDa表达区域:
31-163aa氨基酸序列:
M+RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered PBS, pH 7.4储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.功能2:
Ligand for IL17RA and IL17RC文献:
/研究领域:
Immunology请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验又是代谢的锅,不治之症银屑病终于有盼头了!上交王宏林教授团队Immunity重磅报道
表明与正常鼠相比,PP6 缺陷的角质形成细胞高度增殖,更多地参与髓系细胞和 T 细胞的激活过程。这些结果表明,PP6 缺陷的角质形成细胞将促炎信号转导给免疫细胞。 富集分析表明,在 K5. Pp6fl/fl 鼠的皮损中 TNF 和 IL-17 信号被激活 (图 K)。半定量细胞因子阵列进一步证实了在 K5. Pp6fl/fl 鼠中,IL-23-T17 相关细胞因子的升高,包括 IL-23、IL-12p40、IL-22、IL-20、IL-6、TNF-α、IL-17A 和 IL-17F (图 M)。最后
,以前曾以淋巴细胞活化因子( lymphocyte activating factor)。细胞促进蛋白质( mitogenic protein)以及 B细胞活化因子( B cell- activating factor)等七种名称称之。而 IL2属于淋巴细胞活素,以前曾以胸腺细胞刺激因子( thymocyte stimulating factor)、 T细胞生长因子( T cell growth factor)等六种名称称之。
「铲屎官」注意了!剑桥大学揭示这些基因的改变或让猫猫狗狗成为
细胞 iBMDM 和犬的巨噬样细胞 DH82。结果表明小鼠巨噬细胞感染 2 小时后开始裂解,而犬的巨噬样细胞经过 12 小时仍存活,表明犬的细胞对于鼠伤寒沙门菌的耐受性更高。接着,研究者在小鼠模型上通过 CRISPR-Cas9 技术构建了与 caspase-1/-4 融合蛋白催化作用相当的重组蛋白。小鼠细胞在脂多糖(LPS)刺激下很快裂解,而犬的巨噬样细胞对于 LPS 的刺激则无反应。进一步的体外实验表明,caspase-1/-4 融合蛋白能激活 IL-1β 并且同时切割消皮素 D。图片来源:Cell
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