- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA009892LA01HU
- 2025年07月14日
- ELISA, IHC; Recommended dilution: IHC:1:200-1:500
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Gremlin-1 protein (18-184AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O60565
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:200-1:500
- 浓度：
>95%,Protein G purified
- 靶点：
GREM1
- 抗体英文名：
GREM1 Antibody
- 抗体名：
proliferation inducing gene 2 protein antibody
- 规格：
100μg/50μg/20μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
| 规格： | 20μg | 产品价格： | ￥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验，美国加州基因技术公司（Genentech）的Germaine Fuh和同事突变了HER2的抗体，然后在突变体中筛选出了能够同时绑定HER2和VEGF的变异。这是首次创造出能绑定到2种无关联蛋白的抗体。Fuh说：“这将开启双重标靶型疗法之门。” 重点研发抗体疗法的Genmab生物技术公司副总裁Paul Parren表示，结果令人吃惊。他说：“我们以前根本没有这样考虑过抗体，它让人不禁要猜测，这种分子是否也有可能在自然界中存在。” Variants of the Antibody
Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy
of cardiac hypertrophy. It was accompanied by enlargement of cardiac myocytes and induction of -myosin heavy chain (MHC) and MLC-2 gene expression. Multiple injections of 182-kDa protein-specific polyclonal antibody into the circulation of aorta-constricted
Inducing RNAi with siRNA Cocktails Generated by RNase III
. Figure 1B shows that protein levels were reduced by 78% for GAPDH, 86% for La, and 75% for c-FOS by introduction of the respective siRNA cocktails. These data demonstrate that RNase III generated siRNAs are very efficient at reducing target gene
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