- ￥1100 - 1980
- CUSABIO
- CN
- CSB-PA168659
- 2025年07月12日
- ELISA,WB;ELISA:1:2000-1:5000,WB:1:500-1:2000
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Fusion protein of Human GREM1
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
/
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O60565
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB;ELISA:1:2000-1:5000,WB:1:500-1:2000
- 浓度：
>95%,Antigen affinity purification
- 靶点：
GREM1
- 抗体英文名：
GREM1 Antibody
- 抗体名：
proliferation inducing gene 2 protein antibody
- 规格：
100μl/50μl
| 规格： | 100μl | 产品价格： | ￥1980.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验，美国加州基因技术公司（Genentech）的Germaine Fuh和同事突变了HER2的抗体，然后在突变体中筛选出了能够同时绑定HER2和VEGF的变异。这是首次创造出能绑定到2种无关联蛋白的抗体。Fuh说：“这将开启双重标靶型疗法之门。” 重点研发抗体疗法的Genmab生物技术公司副总裁Paul Parren表示，结果令人吃惊。他说：“我们以前根本没有这样考虑过抗体，它让人不禁要猜测，这种分子是否也有可能在自然界中存在。” Variants of the Antibody
Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy
of cardiac hypertrophy. It was accompanied by enlargement of cardiac myocytes and induction of -myosin heavy chain (MHC) and MLC-2 gene expression. Multiple injections of 182-kDa protein-specific polyclonal antibody into the circulation of aorta-constricted
Inducing RNAi with siRNA Cocktails Generated by RNase III
. Figure 1B shows that protein levels were reduced by 78% for GAPDH, 86% for La, and 75% for c-FOS by introduction of the respective siRNA cocktails. These data demonstrate that RNase III generated siRNAs are very efficient at reducing target gene
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