相关产品推荐更多 >

TMEM59抗体TMEM59兔多抗抗体Liver membrane-bound protein抗体TMEM59 Antibody, Biotin conjugated抗体
¥880
NCOR1抗体NCOR1兔多抗抗体/抗体NCOR1 Antibody抗体
¥2024
KIF6抗体KIF6兔多抗抗体C6orf102Kinesin-like protein KIF6 antibody抗体KIF6 Antibody抗体
¥440
SIRT2抗体SIRT2兔多抗抗体/抗体SIRT2 Antibody抗体
¥2024
KCNMA1抗体KCNMA1兔多抗抗体Slowpoke homolog antibody抗体KCNMA1 Antibody抗体
¥440
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Ephrin-A1 protein (19-182AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P20827
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度:
>95%,Antigen Affinity Purified
- 靶点:
EFNA1
- 抗体英文名:
EFNA1 Antibody
- 抗体名:
Tumor necrosis factor alpha-induced protein 4 antibody
- 规格:
100μl/50μl/20μl
| 规格: | 100μl | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥880.0 |
| 规格: | 20μl | 产品价格: | ¥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验,美国加州基因技术公司(Genentech)的Germaine Fuh和同事突变了HER2的抗体,然后在突变体中筛选出了能够同时绑定HER2和VEGF的变异。这是首次创造出能绑定到2种无关联蛋白的抗体。Fuh说:“这将开启双重标靶型疗法之门。” 重点研发抗体疗法的Genmab生物技术公司副总裁Paul Parren表示,结果令人吃惊。他说:“我们以前根本没有这样考虑过抗体,它让人不禁要猜测,这种分子是否也有可能在自然界中存在。” Variants of the Antibody
:分别是竞争性蛋白质结合分析法[3]、放射性免疫分析法[4]和薄层色谱法[5]。在80年代,放射性免疫分析法得到了广泛的应用和改进,由于这种方法采用放射性核素标记,应用范围受到一定限制,为了进一步提高检测的灵敏度和操作的安全性,进入90年代又陆续发明了各种酶标记法和化学发光法的竞争性ELISA检测试剂盒,这一类检测方法的根本原理都是基于抗体抗原的免疫反应,所有这些试剂盒中采用的抗体全部是兔抗血清或者是经过特异亲和提纯之后的抗cAMP或cGMP的兔多抗,毫无疑问,兔多抗在约四十年的cAMP,cGMP定量
[interleukin (IL)-1β, tumor necrosis factor (TNF)-α and interferon (IFN)-γ]-induced apoptosis. This method is appropriate for subsequent quantification of apoptotic islet cells stained with Tdt-mediated dUTP Nick-End Labeling (TUNEL) and protein expression
技术资料暂无技术资料 索取技术资料





