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- 详细信息
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human VHL. AA range:1-50
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
IHC-p,ELISA
- 浓度:
1 mg/ml
- 靶点:
VHL
- 抗体英文名:
VHL rabbit pAb
- 抗体名:
Von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
- 规格:
50ul
von Hippel-Lindau tumor suppressor(VHL) Homo sapiens Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
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VHL rabbit pAb
¥900







