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MeCP2 rabbit pAb

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  • ¥900
  • AAB
  • 上海
  • A17456
  • 2025年09月25日
  • WB
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic Peptide of MeCP2

    • 形态

      PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB

    • 浓度

      1 mg/ml

    • 靶点

      MECP2

    • 抗体英文名

      MeCP2 rabbit pAb

    • 抗体名

      Methyl-CpG-binding protein 2

    • 规格

      50ul

    methyl-CpG binding protein 2(MECP2) Homo sapiens DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Alternative splicing results in multiple transcript variants encoding different isofor

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    图标文献和实验
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