- ￥900
- AAB
- 上海
- A13216
- 2025年07月10日
- WB
- Rabbit
- Human, Mouse,Rat
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- 详细信息
- 技术资料
- 免疫原：
Synthesized peptide derived from human CXXC4
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human, Mouse,Rat
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1 mg/ml
- 靶点：
CXXC4 IDAX
- 抗体英文名：
CXXC4 rabbit pAb
- 抗体名：
CXXC4
- 规格：
50ul
This gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled, a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin. In addition, the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides, localize to promoters and CpG islands, and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2, an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA. In humans, a mutation in this gene has been associated with development of malignant renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
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CXXC4 rabbit pAb
￥900
