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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥33600.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥23520.0 |
| 规格： | 50ug | 产品价格： | ￥5616.0 |
| 规格： | 10ug | 产品价格： | ￥1872.0 |
Recombinant Mouse Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Val22-Ala196&Met23-Ser335 is expressed.
备注：产品信息可能会有优化升级。请以实际标签信息为准。
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation
成员:Juan Tao, Chunru Jiang, Paipai Guo, Huijuan Chen, Zhenduo Zhu, Tiantian Su, Weijie Zhou, Yu Tai, Chenchen Han, Yang Ma, Jingyu Chen, Wuyi Sun, Yuanyuan Wang, Wei Wei, Qingtong Wang
论文因子:7.419 发表期刊:BIOMEDICINE & PHARMACOTHERAPY pmid:36399825
| 基本信息 | |
| 基因名 | |
| 别名 | SGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 溶解性 | Solube in water |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits，a p19 subunit that is unique to IL-23，and a p40 subunit that is shared with IL-12.The p19 subunit has homology to the p35 subunit of IL-12，as well as to other single chain cytokines such as IL-6 and IL-11.The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors.Although p19 is expressed by activated macrophages，dendritic cells，T cells，and endothelial cells，only activated macrophages and dendritic cells express p40 concurrently to produce IL-23.IL-23 has biological activities that are similar to，but distinct from IL-12.Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells.While IL-12 acts on both naive and memory human T cells，the effects of IL-23 is restricted to memory T cells. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation
成员:Juan Tao, Chunru Jiang, Paipai Guo, Huijuan Chen, Zhenduo Zhu, Tiantian Su, Weijie Zhou, Yu Tai, Chenchen Han, Yang Ma, Jingyu Chen, Wuyi Sun, Yuanyuan Wang, Wei Wei, Qingtong Wang
论文因子:7.419 发表期刊:BIOMEDICINE & PHARMACOTHERAPY pmid:36399825
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
大家知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20o C或-80o C条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04
Th17 Polarization of Mouse CD4 Cells
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