P00225 Recombinant Human Macr

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标题:Talaromyces marneffei suppresses macrophage inflammation by regulating host alternative splicing

成员:Wei Wudi, Wang Gang, Zhang Hong, Bao Xiuli, An Sanqi, Luo Qiang, He Jinhao, Chen Lixiang, Ning Chuanyi, Lai Jingzhen, Yuan Zongxiang, Chen Rongfeng, Jiang Junjun, Ye Li, Liang Hao

论文因子:5.9 发表期刊:Communications Biology pmid:37845378

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标题:SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma

成员:Zhang Yue, Qian Siyu, Wen Qing, Lei Yaxin, Ge Jingjing, Kong Xiaoshuang, Wang Wenhua, Wang Zeyuan, Hou Huting, Tang Canwei, Wu Shaoxuan, Wang Guannan, Li Wencai, Zhang Mingzhi, Zhang Xudong, Chen Qingjiang

论文因子:3.34 发表期刊:Clinical & Translational Oncology pmid:37029239

Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor is produced by our Mammalian expression system and the target gene encoding Ile20-Pro517 is expressed with a 6His tag at the C-terminus.

基本信息
基因名
别名	Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor;CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;CSF1R;FMS
外观(性状)	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF.These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is expressed primarily on cells of the monocyte/macrophage lineage，dendritic cells，stem cells and in the developing placenta.CSF1 and its receptor (CSF1R，product of c-fms proto-oncogene) were initially implicated as essential for normal monocyte development as well as for trophoblastic implantation.It plays an important role in the regulation of osteoclast proliferation and differentiation，the regulation of bone resorption，and is required for normal bone and tooth development.It is required for normal male and female fertility，and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy.Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases，such as rheumatoid arthritis，glomerulonephritis，atherosclerosis，and allograft rejection.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支