Myxochelin A

一种微生物代谢物；在琼脂扩散试验中，80µg/盘浓度下，对革兰氏阳性菌有活性，但对革兰氏阴性菌或真菌无活性；抑制5-LO活性（重组人酶的IC50=1.9µM）；3µg/ml浓度下对26-L5结肠癌细胞有细胞毒性。A microbial metabolite; active against Gram-positive bacteria but not Gram-negative bacteria or fungi in an agar diffusion assay at 80 µg/disc; inhibits 5-LO activity (IC50 = 1.9 µM for the recombinant human enzyme); cytotoxic to 26-L5 colon cancer cells at 3 µg/ml.