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文献和实验Genomic Strategies for the Identification of Dopamine Receptor Genes in Zebrafish
In this chapter, we describe the identification and cloning of D2-like dopamine receptor (DR) genes in zebrafish, a vertebrate model genetic organism. To identify DR genes, we performed searches of the zebrafish genomic sequence database
Transcription Mechanisms for Dopamine Receptor Genes
pharmacologic observations in parkinsonian and schizophrenic patients, the D2 dopamine receptor has traditionally been thought to be the main mediator of the motor and behavioral effects of dopamine (1 ,6 ). More recent molecular and neurophysiologic advances
Dopamine Receptor Binding and Quantitative Autoradiographic Study
of neuropsychiatric disorders such as schizophrenia and Parkinson’s disease. Until 1990, the dopamine receptor population in the brain and periphery was believed to consist of two subtypes, D1 and D2 , which were distinguished by their pharmacology and coupling
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