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文献和实验Genomic Strategies for the Identification of Dopamine Receptor Genes in Zebrafish
In this chapter, we describe the identification and cloning of D2-like dopamine receptor (DR) genes in zebrafish, a vertebrate model genetic organism. To identify DR genes, we performed searches of the zebrafish genomic sequence database
Characterization of Dopamine Receptors
MacKenzie, R.G., VanLeeuwen, D., Pugsley, T.A., Shih, Y.H., Demattos, S., Tang, L., Todd, R.D., and O'Malley, K.L. 1994. Characterization of the human dopamine D3 receptor expressed in transfected cell lines. Eur. J. Pharmacol. 266:79‐85
, the candidate gene in ci3/ci3 rats is the D3 receptor gene (Drd3 ). Lack of D3 receptors has been shown to increase striatal dopamine levels and locomotor activity, so that the reduced D3 receptor expression found in ci3/ci3 mutant rats could explain
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